Some characters from the novel were not featured in the screenplay, whereas some characters were combined into others. The Twilight Saga: New Moon set records for advance ticket sales, causing some theaters to add additional showings.

Kristen Stewart as Bella Swan, a seventeen-year-old girl who moves to the small town of Forks, Washington from Phoenix, Arizona and falls in love with Edward Cullen, a vampire. Summit Home Entertainment's Saturday Release of Twilight Unleashes With Over 3 Million Units Sold" (Press release).Other themes include a bass-line, drum beat and distorted guitar sound for the nomadic vampires, and a melody for the Cullen family.

Elizabeth Reaser was hired as Esme Cullen, despite only knowing in the audition that the film was based on a novel.The settings of certain conversations in the book were also changed to make the scenes more "visually dynamic" on-screen, such as Bella's revelation that she knows Edward is a vampire—this happens in a meadow in the film instead of in Edward's car as in the novel. The role had already been cast by the time the HBO production ended in December 2007, but the selected actor "fell through. On November 22, 2008, one day after the theatrical release of Twilight, Summit confirmed that they would begin working on New Moon. Last time I saw a movie in that same theater, the audience welcomed it as an opportunity to catch up on gossip, texting, and laughing at private jokes.